Mitochondrial copyright 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells

Abstract Cervical cancer is one of the leading causes of cancer death in women.Mitochondrial-mediated ferroptosis (MMF) is Tall Swivel Stool a recently discovered form of cancer cell death.However, the role and the underlying mechanism of MMF in cervical cancer remain elusive.Here, using an unbiased screening for mitochondrial transmembrane candida

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Ending Cervical Cancer Screening in Low-Risk Women After Age 65

Background: Current evidence-based cervical cancer testing guidelines recommend that screening of low-risk women ceases after age 65.Despite this, research suggests that continued testing by primary care providers remains common and represents unnecessary patient discomfort, cost, and consumption of valuable primary care resources.Objective: To und

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The mediating role of health behaviors in the relationship between internal locus of control and life satisfaction in public health students

Abstract Well-being is a continuous process requiring decisions and actions to maintain or build health.This study examines the indirect effect of health locus of control on life satisfaction via healthy behaviors based on living systems theory.Participants were 730 students of various majors related to medicine and health, aged between 19 and 30 (

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An apicoplast-localized deubiquitinase contributes to the cell growth and apicoplast homeostasis of Toxoplasma gondii

Abstract Toxoplasma gondii is among the most important parasites worldwide.The apicoplast is a unique organelle shared by all Apicomplexan protozoa.Increasing lines of evidence suggest that the apicoplast possesses its own ubiquitination system.Deubiquitination is a crucial step executed by deubiquitinase (DUB) during protein ubiquitination.While m

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